noun) in climbing, a rapid move across a rock face in order to reach a hold.
Our mission is to create novel adeno-associated virus (AAV) vectors that enable safe, efficient and targeted in vivo delivery for revolutionary new gene therapies. Our data-driven approach combines next-generation DNA synthesis of millions of AAV capsids with high-throughput sequencing and machine learning. We’re systematically mapping the relationship between capsid sequence and function and optimizing AAV for improved therapeutic efficacy.
We are assembling a multi-disciplinary team of experts on gene therapy, synthetic biology and machine learning, based in Cambridge, MA.